**3DMed 4.4**

In this version, we made the following changes：

1． We added a Endoscopy Slice Navigator plug-in for endoscopy navigation.

2． We added a CUDA Structure Function Volume Rendering plug-in for structure-function two modal volume rendering.

3． We added a CUDA ROI Distance Volume Rendering plug-in for the measurement of the distance from a ROI object to the boundary.

4． We added a CUDA Versatile Volume Rendering plug-in for volume rendering using the versatile optical model.

5． We modified the Volume Crop plug-in to support real-time volume cropping during volume rendering.

6． We modified the volume rendering plug-ins to support endoscopy navigation, bounding-box cropping and illustrative rendering.

7． We added a Hessian Analysis plug-in for hessian-matrix based feature analysis of volume data, currently only a Sheet Filter Operation is provided.

8． We added a new Auto Threshold plug-in which performs the otsu algorithm for threshold segmentation

9． We added a Mask Operation for operations on segmentation masks. Including Complement, Intersection, Union, Mask Extract, Mask Arrange, Bin Open, and Bin Close operations.

10． We added a Target Size plug-in for the measurement of long/short axis of a target object.

11． We added a Flip operation to the Basic Volume Filters plug-in which flips the volume along the y-axis.

12． We added a FFT plug-in for 3D FFT of volume data.

13． We added a CUDA Block Matching plug-in for volume registration.

**3DMed 4.3**

In this version, we made the following changes：

1． We added a new property "source data item" to the data-items in the datalist, in order to register the segmentation results to the source volume.

2． We added a new CUDA Segmented Volume Rendering plug-in for volume rendering of segmented volume data.

3． We added ExportAnalyze / ExportMetaFile / ExportNetCDF / ImportAnalyze / ImportMetaFile / ImportNetCDF Operations to the VolumeIO plugin to support Analyze, MetaFile and NetCDF file formats.

4． We modified the CPUVolumeRendering plug-in, new volume rendering methods added.

5． We added an Option drop-menu to the slice views of the MultiViewVisualization plug-in, so the show/hide of the cross in the view can be toggled.

6． We modified the Threshold-Segmentation plug-in, a histogram and a volume measurement function is added.

**3DMed 4.2**

In this version, we added in two CUDA Based visualization plugins:

1. CUDA Augmented Isosurface Rendering: A CUDA Based Isosurface Rendering plugin with augmented color.

2. CUDA Isosurface Rendering For Big Data: A CUDA Based Isosurface Rendering plugin for big datasets. Augmented color is also supported.

3. GraphCut Segmentation: A volume segmentation plugin based on the Graph-cut algorithm

4. Watershed Panel: A volume segmentation plugin based on the Watershed algorithm